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cape
View on CRAN: Click
here
Download and install cape package within the R console
Install from CRAN:
install.packages("cape")
Install from Github:
library("remotes")
install_github("cran/cape")
Install by package version:
library("remotes")
install_version("cape", "3.1.2")
Attach the package and use:
library("cape")
Maintained by
Anna Tyler
[Scholar Profile | Author Map]
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2013-04-04
Latest Update: 2022-05-19
Description:
Combined Analysis of Pleiotropy and Epistasis infers predictive
networks between genetic variants and phenotypes. It can be used with
standard two-parent populations as well as multi-parent populations, such
as the Diversity Outbred (DO) mice, Collaborative Cross (CC) mice, or the
multi-parent advanced generation intercross (MAGIC) population of Arabidopsis
thaliana. It uses complementary information of pleiotropic gene variants across
different phenotypes to resolve models of epistatic interactions between alleles.
To do this, cape reparametrizes main effect and interaction coefficients from
pairwise variant regressions into directed influence parameters. These
parameters describe how alleles influence each other, in terms of suppression
and enhancement, as well as how gene variants influence phenotypes. All of the
final interactions are reported as directed interactions between pairs of
parental alleles. For detailed descriptions of the methods used in this package
please see the following references.
Carter, G. W., Hays, M., Sherman, A. & Galitski, T. (2012) .
Tyler, A. L., Lu, W., Hendrick, J. J., Philip, V. M. & Carter, G. W. (2013) .
How to cite:
Anna Tyler (2013). cape: Combined Analysis of Pleiotropy and Epistasis for Diversity Outbred Mice. R package version 3.1.2, https://cran.r-project.org/web/packages/cape. Accessed 05 May. 2025.
Previous versions and publish date:
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Complete documentation for cape
Functions, R codes and Examples using
the cape R package
Some associated functions: Cape-class . bin_curve . bin_vector . calc_delta_errors . calc_emp_p . calc_m . calc_p . cape2mpp . center_std . check_bad_markers . check_communities . check_geno . check_underscore . chunkV . colors_from_values . compare_markers . consec_pairs . delete_underscore . direct_influence . draw_pie . error_prop . exp_color_fun . flatten_array . genome_wide_threshold_1D . get_allele_colors . get_block_allele . get_circle . get_col_num . get_color . get_color2 . get_concent_circ . get_covar . get_eigentraits . get_geno . get_geno_dim . get_geno_with_covar . get_interaction_error . get_layout_mat . get_line . get_linearly_independent . get_marker_chr . get_marker_covar . get_marker_idx . get_marker_location . get_marker_name . get_marker_num . get_network . get_pairs_for_pairscan . get_pheno . get_stats_multiallele . hist_pheno . image_with_text . impute_missing_geno . kin_adjust . kinship . linkage_blocks_network . load_input_and_run_cape . marker2covar . my_image_plot . norm_pheno . one_pairscan_parallel . one_singlescanDO . pair_matrix . pairscan . pairscan_kin . pairscan_noKin . pairscan_null . pairscan_null_kin . pheatmap_generate_breaks . pheatmap_scale_colours . pheno2covar . plink2cape . plot_bars . plot_effects . plot_full_network . plot_int_heat . plot_lines . plot_network . plot_pairscan . plot_pheno_cor . plot_points . plot_singlescan . plot_svd . plot_trait_circ . plot_variant_influences . qnorm_pheno . qtl2_to_cape . read_parameters . read_population . remove_ind . remove_kin_ind . remove_markers . remove_missing_genotype_data . remove_unused_markers . report_progress . rotate_mat . run_cape . rz_transform . segment_region . select_eigentraits . select_markers_for_pairscan . select_pheno . singlescan . sort_by_then_by . write_population . write_variant_influences .
Some associated R codes: Cape.R . bin_curve.R . bin_vector.R . calc_delta_errors.R . calc_emp_p.R . calc_m.R . calc_p.R . cape2mpp.R . center_std.R . check_bad_markers.R . check_communities.R . check_geno.R . check_underscore.R . chunkV.R . colors_from_values.R . compare_markers.R . consec_pairs.R . delete_underscore.R . direct_influence.R . draw_pie.R . error_prop.R . exp_color_fun.R . flatten_array.R . genome_wide_threshold_1D.R . get_allele_colors.R . get_block_allele.R . get_circle.R . get_col_num.R . get_color.R . get_color2.R . get_concent_circ.R . get_covar.R . get_eigentraits.R . get_geno.R . get_geno_dim.R . get_geno_with_covar.R . get_interaction_error.R . get_layout_mat.R . get_line.R . get_linearly_independent.R . get_marker_chr.R . get_marker_covar.R . get_marker_idx.R . get_marker_location.R . get_marker_name.R . get_marker_num.R . get_network.R . get_pairs_for_pairscan.R . get_pheno.R . get_stats_multiallele.R . hist_pheno.R . image_with_text.R . impute_missing_geno.R . kin_adjust.R . kinship.R . linkage_blocks_network.R . load_input_and_run_cape.R . marker2covar.R . my_image_plot.R . norm_pheno.R . one_pairscan_parallel.R . one_singlescanDO.R . pair_matrix.R . pairscan.R . pairscan_kin.R . pairscan_noKin.R . pairscan_null.R . pairscan_null_kin.R . pheatmap_generate_breaks.R . pheatmap_scale_colours.R . pheno2covar.R . plink2cape.R . plot_bars.R . plot_effects.R . plot_full_network.R . plot_int_heat.R . plot_lines.R . plot_network.R . plot_pairscan.R . plot_pheno_cor.R . plot_points.R . plot_singlescan.R . plot_svd.R . plot_trait_circ.R . plot_variant_influences.R . qnorm_pheno.R . qtl2_to_cape.R . read_parameters.R . read_population.R . remove_ind.R . remove_kin_ind.R . remove_markers.R . remove_missing_genotype_data.R . remove_unused_markers.R . report_progress.R . rotate_mat.R . run_cape.R . rz_transform.R . segment_region.R . select_eigentraits.R . select_markers_for_pairscan.R . select_pheno.R . singlescan.R . sort_by_then_by.R . write_population.R . write_variant_influences.R . Full cape package functions and examples
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