seAMLessR Documentation

Given the count matrices of bulk-RNA samples, this function deconvolutes each sample into its cell types using a healthy BM reference, and calculates the sample's in vitro resistance to Venetoclax.

Description

Given the count matrices of bulk-RNA samples, this function deconvolutes each sample into its cell types using a healthy BM reference, and calculates the sample's in vitro resistance to Venetoclax.

Usage

seAMLess(mat, verbose = TRUE)

Arguments

mat

count matrix (genes by 1+samples).

verbose

prints detailed messages

Value

List of deconvoluted cell type percentages and predicted drug resistances