R: Objective function for D-optimal OED

detFIM

R Documentation

Objective function for D-optimal OED

Objective function for D-optimal OED

detFIM(x, model, pars)

`x`	a numeric vector of length `n` defining the design matrix. The first n/2 elements are the time points and the last n/2 are the temperatures of these points.
`model`	character string defining the inactivation model to use.
`pars`	list defining the model parameters according to the rules defined in the bioinactivation package.

Numeric value of the objective function for criterium D, which is a determinant of the FIM.

pars <- list(temp_crit = 55,
        n = 1.5,
        k_b = 0.1)
detFIM(x = c(10,15, 20, 25), "Peleg", pars)