Other packages > Find by keyword >

pssmooth  

Flexible and Efficient Evaluation of Principal Surrogates/Treatment Effect Modifiers
View on CRAN: Click here


Download and install pssmooth package within the R console
Install from CRAN:
install.packages("pssmooth")

Install from Github:
library("remotes")
install_github("cran/pssmooth")

Install by package version:
library("remotes")
install_version("pssmooth", "1.0.3")



Attach the package and use:
library("pssmooth")
Maintained by
Michal Juraska
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2018-07-30
Latest Update: 2020-11-18
Description:
Implements estimation and testing procedures for evaluating an intermediate biomarker response as a principal surrogate of a clinical response to treatment (i.e., principal stratification effect modification analysis), as described in Juraska M, Huang Y, and Gilbert PB (2020), Inference on treatment effect modification by biomarker response in a three-phase sampling design, Biostatistics, 21(3): 545-560 . The methods avoid the restrictive 'placebo structural risk' modeling assumption common to past methods and further improve robustness by the use of nonparametric kernel smoothing for biomarker density estimation. A randomized controlled two-group clinical efficacy trial is assumed with an ordered categorical or continuous univariate biomarker response measured at a fixed timepoint post-randomization and with a univariate baseline surrogate measure allowed to be observed in only a subset of trial participants with an observed biomarker response (see the flexible three-phase sampling design in the paper for details). Bootstrap-based procedures are available for pointwise and simultaneous confidence intervals and testing of four relevant hypotheses. Summary and plotting functions are provided for estimation results.
How to cite:
Michal Juraska (2018). pssmooth: Flexible and Efficient Evaluation of Principal Surrogates/Treatment Effect Modifiers. R package version 1.0.3, https://cran.r-project.org/web/packages/pssmooth. Accessed 19 Apr. 2025.
Previous versions and publish date:
1.0.0 (2018-07-30 00:00), 1.0.1 (2018-09-19 22:10), 1.0.2 (2019-01-22 22:50)
Other packages that cited pssmooth R package
View pssmooth citation profile
Other R packages that pssmooth depends, imports, suggests or enhances
Complete documentation for pssmooth
Functions, R codes and Examples using the pssmooth R package
Some associated functions: bootRiskCurve . plotMCEPcurve . riskCurve . summary.riskCurve . testConstancy . testEquality . 
Some associated R codes: pssmooth.R .  Full pssmooth package functions and examples
Downloads during the last 30 days

Today's Hot Picks in Authors and Packages

PCGSE  
Principal Component Gene Set Enrichment
Contains logic for computing the statistical association of variable groups, i.e., gene sets, with r ...
Download / Learn more Package Citations See dependency  
SDT  
Self-Determination Theory Measures
Functions for self-determination motivation theory (SDT) to compute measures of motivation internal ...
Download / Learn more Package Citations See dependency  
MScombine  
Combine Data from Positive and Negative Ionization Mode Finding Common Entities
Find common entities detected in both positive and negative ionization mode, delete this entity in ...
Download / Learn more Package Citations See dependency  
signibox  
Statistical Significance Marks on Boxplots
Add significance marks to any R Boxplot, including a given significance niveau. ...
Download / Learn more Package Citations See dependency  
quickcode  
Quick and Essential 'R' Tricks for Better Scripts
The NOT functions, 'R' tricks and a compilation of some simple quick plus often used 'R' codes to im ...
Download / Learn more Package Citations See dependency  
arsenal  
An Arsenal of 'R' Functions for Large-Scale Statistical Summaries
An Arsenal of 'R' functions for large-scale statistical summaries, which are streamlined to work wi ...
Download / Learn more Package Citations See dependency  

24,012

R Packages

207,311

Dependencies

65,069

Author Associations

24,013

Publication Badges

© Copyright since 2022. All right reserved, rpkg.net.  Based in Cambridge, Massachusetts, USA