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idiffomix  

Integrated Differential Analysis of Multi Omics Data using a Joint Mixture Model
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Download and install idiffomix package within the R console
Install from CRAN:
install.packages("idiffomix")

Install from Github:
library("remotes")
install_github("cran/idiffomix")

Install by package version:
library("remotes")
install_version("idiffomix", "1.0.0")



Attach the package and use:
library("idiffomix")
Maintained by
Koyel Majumdar
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2025-01-13
Latest Update: 2025-01-13
Description:
A joint mixture model has been developed by Majumdar et al. (2025) <doi:10.48550/arXiv.2412.17511> that integrates information from gene expression data and methylation data at the modelling stage to capture their inherent dependency structure, enabling simultaneous identification of differentially methylated cytosine-guanine dinucleotide (CpG) sites and differentially expressed genes. The model leverages a joint likelihood function that accounts for the nested structure in the data, with parameter estimation performed using an expectation-maximisation algorithm.
How to cite:
Koyel Majumdar (2025). idiffomix: Integrated Differential Analysis of Multi Omics Data using a Joint Mixture Model. R package version 1.0.0, https://cran.r-project.org/web/packages/idiffomix. Accessed 03 Feb. 2025.
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