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DRviaSPCN
View on CRAN: Click
here
Download and install DRviaSPCN package within the R console
Install from CRAN:
install.packages("DRviaSPCN")
Install from Github:
library("remotes")
install_github("cran/DRviaSPCN")
Install by package version:
library("remotes")
install_version("DRviaSPCN", "0.1.5")
Attach the package and use:
library("DRviaSPCN")
Maintained by
Junwei Han
[Scholar Profile | Author Map]
[Scholar Profile | Author Map]
All associated links for this package
First Published: 2021-12-09
Latest Update: 2024-01-13
Description:
A systematic biology tool was developed to repurpose drugs via a subpathway crosstalk network. The operation modes include 1) calculating centrality scores of SPs in the context of gene expression data to reflect the influence of SP crosstalk, 2) evaluating drug-disease reverse association based on disease- and drug-induced SPs weighted by the SP crosstalk, 3) identifying cancer candidate drugs through perturbation analysis. There are also several functions used to visualize the results.
How to cite:
Junwei Han (2021). DRviaSPCN: Drug Repurposing in Cancer via a Subpathway Crosstalk Network. R package version 0.1.5, https://cran.r-project.org/web/packages/DRviaSPCN. Accessed 29 Apr. 2025.
Previous versions and publish date:
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Other R packages that DRviaSPCN depends,
imports, suggests or enhances
Complete documentation for DRviaSPCN
Functions, R codes and Examples using
the DRviaSPCN R package
Some associated functions: CalCentralityScore . DRviaSPCN-package . Disease2SPheatmap . Drug2SPheatmap . GetExample . Optimaldrugs . PackageLoaded . envData . getDEscore . getMolecularFm . plotSPW .
Some associated R codes: CalCentralityScore.R . DRviaSPCN-package.R . Disease2SPheatmap.R . Drug2SPheatmap.R . GetExample.R . Optimaldrugs.R . PackageLoaded.R . data.R . getDEscore.R . getMolecularFm.R . globals.R . plotSPW.R . Full DRviaSPCN package functions and examples
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